I just back tested another set of 216 numbers (December 24, 2012 to March 15, 2013). I got 105 hits using List 80, which happens to be 48% of 216. (10500  divided by 216 = 48%).

That is exactly the success rate that ANY set of 80 numbers will give you in the game:

80 x 6 ways = 480 = 48%

So it looks like the other 54% was a fluke.

I have not used the DTD program on this set of 216 numbers, but I suspect that it will be more than 105 hits. I say that because unlike List 80, the DTD program gives you a constantly changing list of 80 numbers based on the numbers you put in, so the numbers tend to be of better quality than the fixed set of numbers that List 80 gives you.  

However, it might be a good idea to give up a few hits in order to have a fixed list that you always play. This way you won’t be dependent on a program for your play list.